1332 results
To discriminate the acquired anti-hormonal resistance phenotypes in patients based on ER expression levels by FES-PET in order to select patients eligible for estrogen therapy.
Is addition of a DPP4-inhibitor (vildagliptin) beneficial in type 2 diabetic patients, starting on once daily long-acting insulin in combination with 2 dd metformin. Primary end point is necessary dose of insulin to remain glycemic control.…
The objective of this study is threefold. The first objective of the study is to determine the course of pervasive developmental disorders (more specific PDD-NOS) and thought problems (more specific MCDD). Secondly, possible processes underlying…
Primary objectivesFor part A of the study: -To determine the feasibility of Clofarabine when given at three possible dose levels together with standard induction cycles I and II in patients with AML/ RAEB with IPSS>=1.5 in a prospective…
The objectives of this study are to examine: (1) the long-term safety and efficacy of alemtuzumab in multiple sclerosis (MS) patients who received alemtuzumab during prior Genzyme-sponsored studies including CAMMS223, CAMMS323, or CAMMS32400507 (…
The objective of this registry is to obtain long-term safety and clinical statusinformation on pediatric patients with IBD (ie, CD, UC, or IC).
To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor…
test the hypothesis that the application of PRP leads to faster wound healing, less wound healing disorders, less pain and faster functional recovery after subacromial surgery.
Primary Objective:To compare the clinical benefit of abiraterone acetate plus prednisone versus placebo plus prednisone in patients with chemotherapy-naïve castration-resistant prostate cancer (CRPC) who are asymptomatic or mildly symptomatic.…
- Evaluation of mean increase in serum creatinine and the incidence of CIN following CT-PA without prehydration compaired to a short prehydration regime with sodium bicarbonate during one hour.- Furthermore, the risk of developing CIN after CT-PA…
In the proposed study we wish to investigate whether orthomanual treatment is of additional value in the treatment of a population of patients with chronic low back pain. We aim to recruit a population that has been referred for evaluation to the…
The objective of the study is to determine whether it is necessary to take the blood pressure lowering medication (β-blocker, ACE-inhibitors or diuretics) of a patient into account prior to blood sampling for pheochromocytoma diagnostics. Therefore…
• Evaluation of the incidence of CIN after CT-angiography with a hydration regime during 1 hour with sodium bicarbonate compaired to a hydration regime with saline during 24 hours.• Furthermore the risk for developing CIN after CT-angiography is…
To evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic LRS.
The first goal of the present study is to elucidate the network topology of the MTL on both large-scale and micro-scale levels with the aim of further understanding epilepsy related changes to the network structure. Additionally we will also use the…
Given the medical need for improved treatment strategies for patients with previously treated and relapsed MM, the purpose of this phase III study is to compare treatment with bortezomib/dexamethasone + panobinostat to bortezomib/dexamethasone +…
Study 11. To determine whether or not there are differences, at baseline, in mTOR activity, between Caucasians and Hindostani, 18-25 years old and healthy on the one hand and middle-aged (40-50 years) with abdominal adiposity on the other hand2. To…
The primary objective of the study is to evaluate the effect of denosumab 60mg every 6 months (Q6M) compared with Actonel 150mg monthly (QM) on total hip Bone Mineral Density (BMD) at 12 months in postmenopausal women transitioning from previous…
Objective: The principal objective is To evaluate the long-term safety and maintenance of efficacy of BOTOX® (200 U) injected into the detrusor for the treatment of urinary incontinence caused by neurogenic detrusor overactivity in patients who have…
This study is designed to demonstrate non inferiority of 150 *g o.d. of indacaterol versus tiotropium 18 *g o.d. with respect to 24 hour post dose (trough) FEV1 after 12 weeks of treatment.