879 results
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
This project aims to understand the symptomatology PD in the light of functional brain interactions, in the hope of elucidating the role of the frontal striatal system to behaviour.
1. To determine the diagnostic accuracy, in terms of detecting a vascular malformation, of CTA, MRI/MRA, DSA, or combinations thereof in patients with ICH?2. To find out which test or combination of tests is most effective for the detection of…
To determine normal values in stress echocardiographic parameters in asymptomatic patients at least 6 months after successful MV repair for organic MV regurgitation. These normal values for non-invasive 2D stress echo testing are of utmost…
The purpose of the project is a) to examine evidence-based instruments (DFSI, ASQ:(SE) and ITSEA) in the Netherlands in practices of midwives and within the system of health care and b) to gain more insight into the role of specific risk- and…
Identification of genetic variations that control monoamine and amino acid metabolism in humans, by translating recent genetic findings in non-human primates to a human cohort.
Establish the clinical value of a molecular sputum test for the diagnosis of lung cancer.
Primary research question:To evaluate the impact of open versus endovascular invasive treatment in different types of surgery (AAA, CEA, LLR) on health status. Secondary research questions:To examine the prognostic impact of quality of life in PAD…
To test if the *analogue patient paradigm* is a suitable methodology to assess effects of communication on patient outcomes. More specifically we aim to test if watching a video of a simulated consultation on a common medical problem leads to…
The current study aims to further our understanding of the relationship between baseline measures - such as impulsivity, working memory and social support - and the effects of enhancing dopamine (via methylphenidate administration) across a wide…
To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone Mineral Content (BMC) and Bone Mineral Density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10…
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
The present study is designed to validate the Dutch IIEF. The psychometric properties of the Dutch version of the IIEF will be investigated.
At CHDR, experience has been gained with the assessment of the in vitro inhibition by MAP kinases of the LPS-induced TNFα release in healthy male volunteers. However, relatively little is known on the inhibition by MAP-kinases in other populations.…
The main objective is to optimize the supplementation of vitamins and minerals to prevent postoperative deficiencies after MB / RYGB or GS on the long term. We also examined whether the number of outpatient visits, blood tests, and costs can be…
We think that the results of this study could be the start of other studies and eventually lead to international standards for treatment of Achilles tendon ruptures.
Aims:a) Understand persistence and/or plasticity of the brain correlatesb) Understand specificity of the brain correlatesQuestions:a) Which neural correlates of OCD are state dependent and thus normalized after successful treatment?b) Which neural…
Goal of this study is to determine if high-field sodium-MRI can be used as:1) a sensitive, in vivo, and non-invasive biomarker to diagnose OA in an early stage and 2) as a method to follow the progression of OA and to monitor the effect of new…
The primary aim of this project is to examine the impact of heart failure on functional sympatholysis.