51 results
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
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To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
Primary Objective: To investigate the effect of treatment with nebulized rhDNase on pulmonary function in children with asthma and persistent obstructive pulmonary function.Secondary Objectives: To investigate the effect of treatment with nebulized…
The purpose of this study is to show that participation in an exercise programme will increase the exercise tolerance, musle power and health-related quality of life and will diminish the degree of fatigue in children on dialysis.
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
Determine whether temozolomide given during radiation therapy followed by the combination of temozolomide and CCNU as adjuvant therapy results in an improvement in event-free survival compared to historical control cohorts.To further assess the…
To elucidate the molecular basis of skin disease.
To show that treatment with SUBLIVAC® Grasses is clinically effective by means of reduction in allergic symptoms and/or use of allergic symptomatic medication in subjects suffering from IgE mediated allergic complaints triggered by grass pollen.
• Evaluation of the safety, tolerability and immunogenicity of subcutaneous (s.c.) administration of ACZ885 in pediatric subjects with SJIA.• Assessment of the initial efficacy profile (% responder to treatment and time to relapse) according to the…
1. To improve patient's quality of life in a cost-effective way by a self-management programme guided by doctors and a specialist asthma nurse through information and communication technology. 2. To investigate whether a simple index of asthma…
The main objective of this research proposal is to 1). develop an on-line monitor for young athletes to prevent them from a systematic overload and to avoid overtraining 2) develop clinical tools to improve diagnostics of overtraining.
Both in emergency departments and in prehospital services (ambulances and MMTs) effort is being done to find a fast alternative for the screw-tipped bone needle that has the least amount of risk and complications.The aim of this study is to analyse…
The primary objective of this study is to specify the executive control processes that contribute to mental inflexibility in persons with autism. The specific part of mental flexibility we are interested in includes processes involved in task…
To prove the efficacy and safety of ethanol lock solution in preventing catheter-related infections and subsequently venous thrombosis in children with a malignant disease who will have a tunnelled central venous catheter inserted.
Objective of the study is to evaluate the long term results of the interventions of the above mentioned deformities.
Now that we have identified the gene underlying the vl mutation and have strong candidates for its genetic modifiers in mouse, we want to investigate their role in human spina bifida. Therefore, our aim is to test GPR161 and its modifier loci for…
Reference values of joint mobility of children in the age 4-18 years.