70 results
Screening causes a difference in prostate cancer mortality of 20% or more.
We hypothesize that the use of low dose gonadotrophin therapy, will prove to be more efficient than CC when used as first line treatment.
N/A
Null hypothesis: sublingual immunotherapy with house dust mite allergen is as effective as placebo on daily symptoms in children with allergic rhinitis.
1. In patients with recurrent vasovagal syncope, current conventional therapy will fail in 40%, after 1 year follow-up. 2. In patients with recurrent vasovagal syncope, treated with conventional therapy and training in physical counterpressure…
To what extent will the introduction of the C-Reactive Protein (CRP) point of care test and enhanced communication skills for managing lower respiratory tract infection (LRTI) in general practice, either separately or combined, lead to 1. an…
The aim of the study is to demonstrate a survival benefit of ICD in patients with high-risk characteristics after primary angioplasty for acute MI.
That laparoscopic surgery alone or in combination with fast track perioperative care is to be preferred over open surgery with standard care in patients having segmental colectomy for malignant disease.
1. Er is geen verschil in kwaliteit van leven wanneer er geen bloedtransfusie gegeven wordt bij een Hb daling van minimaal 1,2 mmol/l en/of een totaal bloedverlies van minimaal 1000ml en een 3,0 ≤ Hb ≤ 4,9 mmol/l indien er geen klachten zijn bij de…
Lenient rate control is not inferior to strict rate control in patients with permanent atrial fibrillation with and without heart failure in terms of cardiovascular mortality and morbidity, neurohormonal activation, NYHA class for heart failure,…
1. Omitting complete inguinofemosal lymphadnectomy in patients with negative sentinel nodes is sufficient; 2. Morbidity associated with the sentinel node procedure is limited; 3. Frozen section, immunohistochemistry and multiple sectioning are…
Rivastigmine is as effective as haloperidol in the treatment of a delirium.
Administration of a higher cumulative dose of temozolomide leads to a higher respons rate in patients with recurrent primitive neuro ectodermal tumors and recurrent high grade gliomas of the CNS, while this treatment does not lead to more side…
Intraventricular infusion of rt-PA reduces the frequency of poor outcome (death or dependency) in patients with a severe intraventricular haemorrhage after aneurysmal subarachnoid hemorrhage.
Test in a phase III randomised study whether an improvement of loco-regional control can be obtained with accelerated postoperative radiotherapy (66 Gy in 5 weeks) as compared to conventionally fractionated radiotherapy (66 Gy in 7 weeks) in…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
1. In patients with a painful arc, treatment with hyaluronic acid and lidocaine, will give a mean improvement of 70 % of their pain at 26 weeks after start of the treatment with subacromial injection as compared to subacromial injection with a…
Previous trials showed that both doxorubicin and thalidomide have anti-tumor activity against hepatocellular carcinoma (HCC). There are indications that these two agents interact synergistically and have non-overlapping toxicity profiles. This trial…
Enzyme therapy with recombinant human alpha glucosidase results in prolonged survival; improvement or stabilisation of cardiac hypertrophy and function, improvement or stabilisation of pulmonary function and improvement or stabilisation of muscle…