2214 results
Primary: To evaluate the long-term safety and tolerability of BIIB017 in subjects originally treated in Study 105MS301 who continue BIIB017 treatment.Secondary: To describe long-term MS outcomes in subjects originally treated in Study 105MS301 who…
This research will explore how fast phonemic restoration of degraded speech can be learned. This will be done by training and testing normal-hearing listeners in several sessions with interrupted speech. We will also train a group of normal-hearing…
OBJECTIVE NOMETEC PART I: "Mapping the lymphatic drainage of the uterus: a feasibility study of the sentinel node procedure"Our aim is to find out which out of two injection methods with technetium labelled nanocolloid is the best to…
To compare the safety, effectiveness and performance of TM ABSORB bioabsorbable everolimus eluting vascular scaffold against XIENCE PRIME TM everolimus eluting coronary stent system in treating people with ischemic heart disease caused by de novo…
Since October 2010 the Catharina-hospital in Eindhoven offers a cardiac rehabilitation program to cardiovascular patients. As an optional section of the program an adjusted training of MBSR is offered, called *stress reduction in cardiovascular…
The primary objective is to assess safety and efficacy of abiraterone acetate plus prednisone and abiraterone acetate plus prednisone plus exemestane, each compared with exemestane alone, in postmenopausal women with ER+ metastatic breast cancer…
Assessment whether the addition of bevacizumab to lomustine improves overall survival in patients with recurrent glioblastoma
To observe a decrease in number of definite and/or suspected pneumonia after prophylactic treatment with antibiotics during CRT in patients with LAHNC.To observe a decrease in the number of admissions in the hospital To observe a decrease in the…
Part 1:The primary objective of the study is to investigate whether treatment with natalizumab slows the accumulation of disability not related to relapses in subjects with SPMS. The secondary objectives of this study are to determine in this study…
To compare the feasibility and safety of surface cooling to 34, 34.5, and 35*C, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours, in awake patients on a stroke unit.
The aim of this study is the investigate genetic and environmental factors which make a person vulnerable to develop a pychosis and (in patients) affect the progression of a psychosis. A second objective is to investigate the effects of genetic and…
This study is aimed at determining pharmacokinetics and pharmacodynamics of medications routinely used at the Erasmus Medical Centre in pediatric cardiac surgery during and after cardiopulmonary bypass. The goal is to be able to formulate evidence…
The overall objective of the MOBI-KIDS study is to assess the potential carcinogenic effects of childhood and adolescent exposure to RF and ELF from mobile telephones on the central nervous system (CNS). In order to achieve the overall objective,…
To compare the efficacy of early decompressive surgery to improve functional outcome in patients with cevical incomplete cord lesion without a fracture or instability of the cervical spine compared to those receiving conservative treatment.
The primary objectives are:- To evaluate the efficacy of IV induction regimens of ustekinumab in inducing clinical response in subjects with moderately to severely active Crohn*s disease.- To evaluate the safety of IV induction regimens of…
The main aim of this study is to find out if the continuation of bevacizumab, in addition to standard 2nd & 3rd -line treatment, can help patients with NSCLC that has progressed to live longer. The study also aims to find out if continued…
usefulness of I-FABP in the surgical managment of small bowel obstruction caused by adhesions.
The primary objective of this study is to determine whether the Impella cVAD device vs. IABP therapy leads to a higher 30 day survival rate in shock STEMI patients in the setting of primary PCI.
Primary objective: The primary objective of the study is to evaluate the dose-response of tofacitinib in inducing clinical remission in subjects with moderate to severe Crohn*s disease and to select effective doses. Secondary objectives: -To…
Effectiveness: To provide valid scientific evidence that use of the TactiCath® Set is an effective treatment for symptomatic paroxysmal atrial fibrillation (PAF).Safety: To provide valid scientific evidence that use of the TactiCath® Set is safe as…