188 results
The primary objective of this study is to investigate if shear-wave elastography and contrast-enhanced ultrasonography can identify those patients most suitable fir an intervention (surgery or endoscopic balloon dilation) and those patients that…
Thermoregulation in patients with spinal cord injury and cold sensations, an explorative pilot-study
To investigate whether SCI patients with regular complaints of cold sensations in daily life have more impaired thermoregulatory responses to changes in environmental temperature compared to SCI patients who do not have these cold sensations in…
To assess the presence of absence of ILCs in preclinical (early) pSS biopsies as well as to assess their potential interaction with epithelial cells.
The primary aim is to assess myocardial development and function of the left ventricle in fetuses with the suspicion of aortic coarctation on fetal echocardiography. The secondary aim is to study left ventricular blood flow movement with vector…
The study aims to quantify differences in gastric digestion and absorption of caprine and bovine casein protein
Objective: Study 1: T0 case-control observational study1) Explore if the failure to speak in specific social situations is associated with social anxiety as expressed by autonomic emotional arousal.2) To assess if the failure to speak in specific…
1. What is the level of psychological distress among cervical cancer patients over time?2. What is the role of characteristics of the individual, characteristics of the environment, biological function, overall quality of life, functional status and…
1) Establish a comprehensive clinical and antibody profile of autoimmune synaptic encephalitis in dementia syndromes. 2) To assess outcome and provide diagnostic guidelines who to test and in whom testing will be unnecessary, and elucidate…
1] To explore the course of performance-based physical functional recovery at ICU admission, hospital discharge, three months post-hospital discharge and at six months post-hospital discharge of ICU survivors who have been * 48 at mechanical…
We aim to investigate the predictive value of the wheezing phenotypes EVW and MTW at preschool age (based on prospectively reported symptoms of wheezing, dyspnoea and cough or based on clinical assessments) and the predictive value of viral upper…
The objective is to characterize intrarenal T cells isolated from transplant biopsies both phenotypically and functionally.
Objectives: 1) The development of an optimal point-of-care (POC) breath test for an early asthma diagnosis in preschool wheezing children; 2) To unravel important pathogenetic mechanisms in the early development of viral wheeze and asthma by…
To compare young and old COPD immunologically, physiologically, risk factors, patient behaviour and quality of life.
The main objective is to pinpoint the biological pathways that set long-term risk of CVD and NDI when epigenetically disturbed during fetal development by (1) establishing a longitudinal cohort of MC twins, (2) defining epigenetic alterations…
To collect data in order to create a registry that can be used for research in PXE, partly with an international questionnaire, and to measure PPi, ENPP1 activity, anti-retinal antibodies and cytokines, and retinal calcification in all patients…
* To examine the effects and interactions of individual and environmental factors on the onset and course of mental health problems in adolescents and young adults. * To examine the effects and interactions of individual and environmental factors on…
To initiate a Dutch cohort with standardized follow-up measures and investigating blood, liquor, urine samples and nailfold videocapillaroscopy findings for prognostic factors during disease quiescence and at times of disease flare. This will…
To study the differences in MI between short-term ill adolescents with AN (< illness duration 1 year) and patients who started their illness in adolescence and have been ill for at least 5 years consecutively and with healthy controls. A…
Despite seeing an increase in children admitted to the paediatric intensive care unit for severe acute asthma, we still do not know what the cause of this increase is, and we still only have few drugs we can give these children, regardless of the…
In the present randomised double blind controlled study, we will study the effects of GOS or FOS vs a placebo on stool consistency. Other parameters to be investigated include stool frequency, stool consistency in number of cases (%), painful…