135 results
The primary objective is acquiring insights in the development of BOS in patients after human lung transplantation in an early phase of the disease which can be used to improve immunotherapeutic handling in order to prevent or delay the onset of BOS…
In this study the prevalence and kind of sexual and psychosexual problems will be assessed. Psychological well being is studied as well
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
To obtain insight in the role of the innate immune response, especially Type 1 interferons, in the pathogenesis of RSV LRTI. New techniques are used to unravel the local (nasopharyngeal) immunological milieu during viral LRTI. The hypothesis is that…
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
To examine cellular damage, intestinal barrier function loss, activation of the Complement system and inflammatory alterations induced by ischemia and reperfusion of the human small and large intestine.Second, we aim to study the consequences of…
1) To assess whether galactosemia women with ovarian failure are able to produce estradiol after exogenous (normally bioactive) FSH and LH gift 2) To characterize FSH glycan structures
In previous studies we have identified specific receptor and surface protein expression profiles on neutrophils. Some of these profiles point at partially refractory neutrophils. In the current NERTHUS study we have seen that circulating neutrophils…
The two objectives of our proposal are: (i) to identify specific gene expression profiles in blood and fibroblasts from patients with ALS or ALS-mimic in order to improve diagnosis and measure disease progression; (ii) the identification of genetic…
Objective of this study is to provide evidence for the induction of AGEs in blood and tissue in patients with septic shock.
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
Investigate effect of IF on insulin resistance and possible role acylcarinitin profiles and glycolipids
This study will be focused on the executive functioning of PD patients and the associations between effort, motor symptoms, depression and the executive functioning of PD patients. By investigating to what extent executive dysfunctions in PD are…
Our objective is to study the changes in cytokine levels in dermal interstitial fluid (ISF) obtained by a minimally invasive technique after single and repeated sodium lauryl sulphate (SLS) exposure compared to untreated skin. The study will give…
To elucidate the molecular basis of skin disease.
The purpose of the present study is to clarify the assumed role of fear in women with superficial dyspareunia. The hypothesis will be tested that aversive conditioning in women with dyspareunia and control women will lead to diminished sexual…
To determine, by measuring cIMT's, whether the abnormal lipid profile of GD I carriers and patients is associated with atherosclerosis and an increased risk of CAD.
The objective of the current study proposal is to gain insight in the effect of pulmonary vein isolation on the electrophysiological properties nearby the ablation lines on the posterior sight of the left atrium and further away, especially in the…
1. The central hypothesis of this study is that genetic polymorphisms in drug metabolising enzymes and regulators of enzyme expression may predispose to ATDH. We propose to evaluate the presence of genetic polymorphisms among TB patients in…