269 results
To establish the diagnostisch accuracy of ultrasound for the exclusion of fracture of the elbow
The detection rate of the ICG method to identify the SLN in breast cancer patients is not inferior to the standard 99mTc method.
Extracellular vesicles (EVs) in plasma can be used as a biomarker for stroke diagnosis, thereby discriminating between ischemic and hemorrhagic stroke.
We hypothesize that functional Near Infrared Spectroscopy (fNIRS), eye-tracking, Indirect Calorimetry (IC), the BOD POD, and Bio-Impedance Analysis (BIA) are feasible outcome measures for children with Angelman syndrome.
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
PCT-guided treatment regarding antibiotic use is non-inferior to usual care consisting of prednisolone and or antibiotics, in terms of treatment failure at day 30 for patients hospitalized because of an acute exacerbation of COPD (AECOPD).
The hypothesis investigated is that a correct diagnosis (including subclassification of the tumor) and prognosis can be made more rapidly and that monitoring tumor development in response to therapy is more precise when adding tumor markers to the…
Our main objective is to develop and validate body fluid biomarkers that detect CAA in Alzheimer*s Disease patients during life.
To assess accuracy of 18F-sodiumfluoride (NaF) positron emission tomography (PET) and serum non-oxidized parathyroid hormone (PTH) as an accurate, reliable and easy applicable diagnostic tools for the assessment of bone turnover in chronic kidney…
Determining the robustness of [18F]-FDG PET/CT based quantitative features in metastatic melanoma patients by test-retesting [18F]-FDG PET/CT scans and varying post processing scan settings, for future diagnostic and prognostic clinical application.
Therefore, in this study, we would like to investigate the clinical effectiveness of a smart technology intervention (The Heart Failure Box) in heart failure patients from the department of Cardiology at Leiden University Medical Center.
To determine if stimulated salivation during the biodistribution of PSMA-ligands causes a significant increase in the accumulation in salivary glands
Primary objective: 1. To establish whether obtaining CTCs of mHSPC patients by DLA for single cell genotyping and phenotyping warrants further clinical exploration. Secondary objectives: 1. To investigate the number of CTCs in peripheral blood of…
In this study we aim to evaluate whether the levels of TRAIL and/or IP-10, alone or in combination, are a sign of viral infection at a stage before symptoms arise. We will assess the diagnostic value of the biomarkers alone and/or in combination,…
To investigate the prevalence of transthyretin amyloid cardiomyopathy in HFpEF patients with a cardiac implantable electronic device (CIED) such as a pacemaker or Implantable Cardioverter Defibrillator (ICD)
Research directionUntil now only the tumor has been part of the search for new molecular imaging targets. The associated microbial biofilm that is present on 89% of right-sided CRCs and conventional advanced adenomas (CAAs) has so far not been…
To study the clinical value of pressure and flow assessment for predicting treatment response to PTRA and validate the pressure gradient assessment by CFD in patients with available CT angiography.
It is currently common practice to perform diagnostic wrist arthroscopy in patients suspected of scapholunate instability (SLI). This is an invasive, relatively expensive and non-dynamic approach. Small lesions or dynamic dysfunction of the…
The primary objective of this study is to characterize low-voltage substrate, as identified via HD Wave mapping in sinus rhythm and identify associations with 12-month recurrence rates after a single pulmonary vein isolation with a contact force RF…