297 results
The primary objective is to determine the impact of HER2 expression in CTCs taken at baseline on outcome to AIs in metastatic breast cancer patients with an ER-positive primary tumor. Secondary objectives are to determine impact of HER2 expression…
The main objective of this study is to evaluate whether earlier establishment of Critical View of Safety can be obtained during laparoscopic cholecystectomy, by applying NIRF laparoscopic imaging as an adjunct to conventional laparoscopic imaging…
Obtain normative data within similar age-range as our clubfoot patients.
The primary objective is to investigate the neural correlates of the integration of multisensory information in adolescents with ASD.
To examine whether providing feedback to patients immediately after scoring in a non-valid range on a SVT would have an impact on subsequent symptom validity and neuropsychological test performance. Furthermore, we examine treatment-outcome as a…
Primary: To identify whether PCR-proven rhinovirus is a risk factor for prolonged PICU admission in children undergoing cardiac surgery. Secondary: to develop a preoperative algorithm to identify children with increased risk for prolonged PICU…
To determine whether AFOs optimized for stiffness in patients with calf muscle weakness are superior to standard AFOs in reducing walking effort, as measured by energy cost of walking (ECW, in Jkg-1m-1), and 2) to build a model to predict required…
To assess whether atrial flow patterns during sinus rhythm in patients with atrial fibrillation differ from healthy controls with sinus rhythm.
Primary objective:- To develop a patient-specific adaptive radiotherapy planning strategy using MRI with more precise target coverage and critical organ sparing by safely reducing treatment margins for resectable esophageal cancer irradiation.…
Primary: How does the diagnostic outcome of the digital PET/CT study compare to the outcome of conventional PET/CT in patients referred for (re)staging of lung cancer, breast cancer and a group of miscellaneous cancers?Secundary: What is the image…
To explore whether patients with SCN9A-associated SFN have an abnormal brain activation pattern on resting state fMRI and altered structural connectivity on DTI versus age- and gender-matched healthy controls. With this knowledge, objective pain…
To investigate whether it is possible to indicate (focal) IF/TA lesions in renal allografts with MRI and compare these findings to the extent of IF/TA in the kidney biopsy that has been taken previously according to current clinical guidelines.
Primary objective: To evaluate the efficacy of MPDL3280A in patients with locally advanced or metastatic solid tumor whom, in the opinion of the investigator, based on available clinical data, may benefit from treatment with anti PD-L1 immunotherapy…
The main objective of this study is to biochemically and histologically validate two novel MRI techniques to characterize myocardial properties that are expected to be useful for the diagnosis of various forms of cardiomyopathy. A second objective…
Assessment of coronary artery disease (plaque and stenosis) by low-dose coronary Computed Tomography (CCT), with both non-contrast CT for coronary artery calcium scoring (CACS) and contrast-enhanced CT coronary angiography (CCTA) and additionally a…
Objectives: 1. The first objective is to determine the nature and spatial distribution of sonographic abnormalities in CIAP and in CIDP, MIDN and MMN. 2. On the basis of the findings in objective 1, we will define a standardized HRUS research…
The use of multiple programs programmed on the CI processor will be compared to the automatic scene analyser (SCAN). The possibilities of performing speech intelligibility tests at home will be examined and implemented in a webbased environment, and…
The primary goal of this study is to evaluate the effect of varying stimulation parameters (inter-phase gap, phase duration, en inter-pulse interval) on the nerve and brainstem response and to correlate this to speech perception performance with the…
The objective of the study is to develop a whole blood cell-mediated immunity test for Borrelia infection and investigate whether such a test can detect Borrelia infections more reliably than the currently used antibody tests in the early stage of…
Aim of the PRECious trial is to evaluate the effect of a standardized postoperative algorithm for quality control (via standardized measurement of CRP levels and CT-scan imaging) on morbidity and mortality after major digestive surgery.