312 results
The objectives of this study are:1. to evaluate the occurrence and distribution of structural brain changes in HHT patients with and without pulmonary AVMs as compared to healthy age matched controls;2. to evaluate the (autoregulatory) function of…
Main objective: investigate the correlation between CAP-values with fat percentages found at 1H-MR Spectroscopy and steatosis grade at liver biopsy. Secondary objectives: investigate the reproducibility of CAP-measurements; investigate the…
The aim of this pilot-study is to examine the accuracy of MRL compared to current nodal staging methods. We expect anacceptable accuracy of the MRL based on earlier studies with gadofosveset enhanced MRI in rectum cancer patients. Then the MRL could…
This large prospective multi-center cohort study aims to identify patient*s characteristics that significantly influence ovarian response to mild stimulation with a fixed dose of 75 IU recombinant FSH
The primary objective (on lesion-based analysis) is to show that pre-treatment 89Zr-trastuzumab PET/CT is able to select lesions not responding morphologically from treatment with T-DM1 (applying RECIST 1.0 criteria)Secondary Objectives and…
Primairy objectives:1.To investigate whether a non-invasive imaging guided strategy (either CTA or CMR) early in the diagnostic process reduces the number of patients with at least one ICA during the initial admission as compared to routine clinical…
1. To improve the overall outcome as compared to the previous protocols of the DCOG, especially ALL-9 and ALL-10.This is aimed for by decreasing therapy for part of the patients (TEL/AML1, Down syndrome, PPR only), increasing therapy for IKZF1…
This study will investigates the effect of high dose alkylating chemotherapy compared to standard dose chemotherapy as part of a multimodality approach in patients with oligometastatic HRD positive and/or BRCA1/2 related breast cancer.
Primary Objective: To show that an integrated chronic care program in a specialized AF clinic reduces cardiovascular hospitalizations and mortality.Secondary Objective(s): 1) To demonstrate the benefits of an integrated chronic care program in terms…
1) To study whether local inflammation is present in patients with Clinical Suspect Artralgia and detectable with dedicated extremity MRI2) To identify determinants (imaging but also serological, genetic factors) for progression to clinical…
To develop a prediction model for women with one previous caesarean section by combining assessment of the lower uterine segment with an extensive antepartum history taking and postpartum follow up.
[Retrospective clinical path:1) main objective: to identify predictors (sociodemographic, clinical, imaging, and (neuro)psychological variables) of objective cognitive functioning of all patients who undergo neurosurgyer, at 3 months after surgery2…