280 results
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
* To study the relationship between inflammation on MRI and syndesmophyte formation with very detailedimaging methods: radiography, computed tomography (CT), 3 and 7 Tesla MRI. * To examine the time order of pathologic changes like inflammation,…
To study the quantitative and qualitative relationship between a heat stimulus and the vasomotor response in healthy subjects and to determine the feasibility of this measurement setup for patients.
The aim of this project is to assess whether 4D-CTA can generate 3D cranial image data sets with sufficient spatial and temporal resolution to enable its use as a diagnostic tool in cerebrovascular pathology and physiology such as arteriovenous…
Part I of the study: I) to determine if one or a batch of aging marker(s) is/are associated with the presence of objectively diagnosed COPD related co-morbidity (muscle wasting, osteoporosis, cardiovascular risk, glucose intolerance, renal failure,…
1. Evaluation of gene-expression profiles of endometria of PCOS women compared to normal ovulatory women2. Identify genes and pathways which contribute to a high rate of miscarriages of PCOS women3. Identify genes and pathways related to the high…
Primary Objective: To study the arginine-NO metabolism during fracture healing and dysfunctional fracture healingSecondary Objective(s): To investigate if differences or decreased arginine and NO concentrations in bone healing form a prognostic…
Primary goal of this study:1) To determin the percentage of structural damage caused by an ankle inversion trauma. 2) Investigate to which patient characteristics, anamnestic characteristics, physical examination and structural characteristics…
The present study will test 1) whether childmolesters (including childpornography downloaders) show ASD symptoms, like disturbances in recognizing other*s emotions, feelings, intentions and thoughts, lack of interpersonal skills empathy deficits and…
The present research protocol aims at the development and implementation of a valid self-report instrument for suicidality amongadolescents. The instrument needs to be invariant for ethnicity and needs to register fluctuations in suicide risk and…
1. To construct a Dutch multicenter prospective biorepository for validation of biomarker and imaging products.2. To provide a Medical Technology Assessment (MTA) of newly developed biomarkers, contrast enhanced ultrasound and multimodality MR Iin…
To investigate the dynamics of tumour hypoxia as assessed by 18F-FAZA PET/CT during and after chemoradiotherapy. To investigate the best strategy to deliver a boost dose to the hypoxic tumour areas. This strategy may be either a simultaneous boost (…
Primary objective: to compare glucose profiles collected by CGM on days with and without haemodialysis in a group of insulin treated diabetic patients who are on regular hemodialysis treatment. Secondary objectives: o assessment of frequency and…
The goal of this study is to perform an analysis of the ability of the different combinations of MRI technique/stimulation delivery to measure the cerebrovascular reactivity. In this study only the following stimulations will be used for the…
1. To investigate the feasibility of photoacoustic breast cancer imaging as embodied in the first generation photoacoustic mammoscope; 2. To correlate the photoacoustic images to conventional diagnosis of the breast and therefore to find…
To determine whether the use of epinephrine saline irrigation in therapeutic shoulder arthroscopy with need for subacromial procedures should significantly increase clarity of the view.
1. To image tissue biodistribution (joints, lymph nodes and internal organs) of rituximab in RA patients by [89Zr]rituximab PET-CT in RA patients with clinically active disease that will start rituximab treatment.2. To investigate whether…
The aim of this prospective study is 1) to evaluate the diagnostic efficacy of DBE in comparison to MRE as surveillance technique of the small-bowel in PJS patients, 2) to analyze patient burden and quality of life with DBE and MRE, and 3) to…
In this study we will evaluate the diagnostic value of ultrasound in patients presenting without clinical observable synovitis at firstconsultation compared to de clinical diagnosis by the rheumatologist in the 12 month follow-up of this study.
The primary aim of the study is the validation of the dermatoscope as a diagnostic aid for analyzing patients who visit the GP with the suspicion of a skin malignancy.Secondary aims of the study are the determination of the extent of health care…