80 results
The primary objective of this intervention study is to examine in abdominally obese men the acute effect of inorganic nitrate as compared with placebo on brain insulin-sensitivity, as assessed by the gray-matter CBF response to intranasally…
Primary objective: To reduce absenteeism among HCW with direct patient contacts during the epidemic phase of COVID19. Secondary objective: To reduce hospital admission, ICU admission or death in HCW with direct patient contacts during the epidemic…
The objective of this study is to demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of periproceduralstroke (*72 hours) after transcatheter aortic valve replacement (TAVR).
This study aims to further reduce the incidence of a post-ERCP pancreatitis by administrating a single gift antibiotics after the procedure.
To determine the impact of BCG vaccination on the incidence of clinically relevant respiratory infections or COVID-19 in vulnerablel older adults.
The objective is to validate the NESTORE Platform in relation to three main evaluation criteria: For (1) Feasibility, we will evaluate the validity and the appropriateness of the procedures for the proposed intervention. For (2) Usability and (3)…
This pilot does not aim to demonstrate the effectiveness of the system. The effectiveness of the system has been demonstrated in the recently published study: Chromed study, a multi-center Randomized Controlled Study.This pilot aims to obtain…
This study has a strong explorative and qualitative approach and set-up. Please note that the goal of the study is to further identify possible areas for innovation for professionals, patients and their partners. The aim for this study is NOT to…
Gaining information on the dynamics and shape of the stent graft and stented target vessels, and how these change over time will improve our understanding about the fixation and/or sealing of the stent graft, which may help in stent graft selection…
The aim of this study is to obtain further knowledge on aerosol droplet formation and spread during oxygen therapy.
The aim of the current study is to determine whether a *liberal* strategy of maintaining Hb concentrations above 9 g/dL would result in a different neurological outcome when compared to a *restrictive* approach to red-cell transfusion to avoid…
The objective of this project is to identify a well consumable butyrate/hexanoate-enriched oil that increase circulating SCFA levels and improves postprandial substrate metabolism. We will investigate the effects of acute intake of four different…
To assess the change in Intra-Abdominal Pressure (IAP), measured via indwelling urinary catheter, when using the IPS for positioning a subject in prone position for spine surgery.
Prior to conducting an RCT to study the efficacy of STAIRS, we conduct a pilot to (1) investigate the usability, feasibility and acceptability of the program and (2) to investigate the feasibility and acceptability of the intended measurement method…
The primary objective is to determine the effect of ICU-VR at three months after discharge on psychological sequelae and HRQoL up to 6 months after discharge in patients treated for COVID-19 on the ICU. The secondary objective is to determine the…
To assess risk factors for cardiomyopathy and heart failure among lymphoma (HL and aggressive B-cell NHL) survivors, focusing on the independent and joint effects of doses of anthracycline-containing chemotherapy (doxorubicin) and rituximab as well…
The effectiveness of an e-health intervention will be tested by means of a randomized controlled trial. The control condition consists of psycho-education on pregnancy, stress and smoking. The primary outcome measure is smoking (frequency of women…
- To evaluate the effect of hydroxychloroquine treatment on the endosomal TLR response in young and elderly healthy male volunteers- To evaluate the effect of hydroxychloroquine treatment on the general T and B cell activity (proliferation,…
To determine whether 12 weeks of GABA supplementation versus placebo supplementation can improve oral glucose tolerance in people at risk of developing type 2 diabetes and explore the effects of GABA on overall metabolic health.
It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…