112 results
The objective of the PANDORINA trial is to evaluate the non-inferiority of omitting routine intra-abdominal drainage after DP on postoperative morbidity (Clavien-Dindo score ≥ 3), and, secondarily, POPF grade B/C.
1) To investigate the effect of either the consumption of 1 or 3 small meals compared to no meal during the night shift on alertness levels, gastrointestinal complaints and glucose levels. 2) To investigate the effect of low glycaemic loaded meal(s…
To determine which patients, individually classified for VTE ánd bleeding risk, will benefit from prolonged anticoagulant treatment without being unnecessarily exposed to its risks.
Treatment with Venoruton prevents RVO, which is a surrogate outcome of PTS.
In this study we would like to investigate the clinical effectiveness of a smart technology intervention (The Heart Failure Box) in heart failure patients from the department of Cardiology at Leiden University Medical Center.
The two main objectives are: A) identify patterns of psychofysiological stress in staff and clients prior to challenging behaviour, and B) explore possibilities of biofeedback on the psychofysiological stress level of staff, and whether biofeedback…
We want to examine whether a semi-acute mindfulness based stress reduction (MBSR) intervention, specifically tailored to fit the needs of the health care workers and crisis situation, in addition to support as usual (SAU) can prevent incident/…
To draw definite conclusions about the effectiveness of omega-3 PUFA supplementation in anorexia nervosa patients a double-blinded, placebo-controlled randomized controlled trial (RCT) with a substantial sample size should be conducted. Prior to…
It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…
This pilot study is designed to evaluate the feasibility of field activities and if necessary adjust the methods for the full-scale study. Primary Objective: to evaluate the recruitment, retention and compliance rates for a prospective cohort study…
* To measure the quality of the red blood cells of redon drain blood before and after cell saver processing.* To measure the effects on whole redon drain blood in terms of inflammatory activation, platelet activation and blood rheology in the…
We aim to investigate the effectiveness of implementation of a TPS compared to standard of care (SOC) for patients at risk of developing CPSP, as measured by quality of recovery, incidence of CPSP and opioid consumption.
A stepped-wedge cluster randomized trial with a clear aim to demonstrate the clinical outcomes, the mechanistical effect and the cost efficiency of prehabilitation across a wide range of patients, diseases and procedures.
1)to gain insight into the prevalence of HIV and other STDs among transgender people. 2) to identify determinants that are associated with HIV and STD presence (through optional questionnaires).
Primary objective: To reduce clinically relevant respiratory tract infections (including COVID-19) ind community dwelling older persons during the pandemic of SARS-CoV-2. Secondary objective: To reduce disease severity, the duration of hospital…
Primary objective:Does the use of the application support a positive lifestyle development?Secondary objectives:Does the use of the application support an increase in physical activity levels?Does the use of the application has a positive influence…
To study the effectiveness and safety of administration of FMT on acute pouchitis.
To assess the effectiveness of an intervention aiming at increase of sunscreens use in outdoor workers. Furthermore, to assess external UV-exposure and prevalence of NMSC including actinic keratosis (AK).
Main objective of the trial is to determine the effect of individualizing the immunosuppressive therapy based on baseline immune-risk stratification according to 2 new biomarkers (d-sp ELISPOT IFN-γ and donor/recipient HLA Eplet Mismatch), in a…
The primary objective of this study is to investigate the effect of a six-week period personalized food intervention with prebiotic supplementation on intense exercise performance in healthy, recreationally active adults. Further, this study has…