113 results
1. To determine the influence of frailty on predicting an increase in HRQL in elderly cardiac surgery patients .2. To develop an AGE score for predicting an increase in HRQL after cardiac surgery based on surgical risk factors, comorbidities and…
The exact mechanism behind these dietary influenced modulations of the composition of gut microbiota is unknown. Our hypothesis is that dietary fat intake indirectly causes alteration of the gut microbiota composition, by affecting the function of…
Part 1: Main objective: Investigate the relation between level of physical (in)activity and cognition in healthy elderly and to examine the possible moderating effects of (Apolipoprotein E e4) APOEe4 status and IGF-1 and BDNF levels and blood…
The OPTIMAL cohort aims to describe the quality of life and pain perception of patients after local treatment (radiotherapy and/or surgery) of metastases of the long bones, for both the entire cohort as well as for specific treatments separately.…
The aim of our study is to investigate the effect of sirolimus on the progression of intestinal adenomas in patients with FAP and to assess the safety of this treatment.
We are interested to see whether a sulforaphane enriched diet will improve post-operative recovery in healthy patients who donate a kidney for the purpose of a kidney transplantation.
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-12 years with…
The primary aim of this study is to understand the neurocognitive mechanisms by which preventive cognitive therapy obtains its preventive effects in remitted depressed patients. Using functional MRI in combination with pupillometry and…
We aim to assess whether aerobic exercise leads to increased cerebral perfusion in patients with vascular cognitive impairment.
To evaluate the long-term effects of GH-therapy on metabolic profile and risk factors for cardiovascular diseases in adults (aged 25-35 years) born SGA and compare this with non-treated adults born SGA and with adults born AGA.
To investigate whether deep and slow breathing exercises can reduce pain induced by mobilizing from bed to chair after major abdominal surgery, compared to a reading task.
Optimizing (breathing) techniques for radiotherapy of esophageal and lung carcinomas; a pilot study.
Primary objective: To determine the optimal breathing technique to minimize the dose to the heart of radiotherapy for esophageal and lung cancer using current photon techniques, without compromising the dose to the lungs. Secondary Objectives: 1. To…
Primary objective: To assess the impact of a low glycaemic load (GL) diet as compared to a *Western* diet on metabolic flexibility (the change in RQ) upon a hyperinsulinemic euglycemic clamp. Secondary objectives: 1) To assess the impact of low GL…
Primary ObjectiveThe primary objective for this study is to compare the clinical efficacy of weekly abatacept in combination with methotrexate to methotrexate alone in achieving Remission, defined as SDAI less than or equal to 3, at Week 24.…
To evaluate the effect of AMG 334 compared to placebo on the change from baseline in mean monthly migraine days, in subjects with episodic migraine.hypothesis: In subjects with episodic migraine, AMG 334 has a greater reduction from baseline in mean…
The main aim of this phase-II-proof-of-principle study is to test whether the health game AquaSnap offers improvement of cognitive impairment in PD patients with mild cognitive impairment, using an RCT. The long-term ambition is to test whether the…
The primary objective of this study is to investigate the relationship between diet composition, meal timing, and meal frequency with cognitive performance in nurses during a night shift setting.Secondary objectives of this study are 1) to…
Primary Objective: To examine how protein supplemented after exercise and before each night of sleep augments the resistance type exercise training-induced changes in quadriceps muscle size (CSA) in healthy elderly men. Secondary Objective:…
The main goal of the current project is to study whether a mindset of perceived control / loss of control over intake affects hormone release, brain reward processing, desire to eat and actual consumption.
To assess the efficacy of a TCC, a BTCC and a cast shoe with similar plantar soles on offloading the previous ulcer location in people with DM and peripheral neuropathy.