137 results
Primary Objectives: - DirectLifeDirectLifeAre the LiveWorkout® and DirectLife® concept feasible web based training programs for type 2 diabetes patients ?- How do type 2 diabetes patients experience web based training intervention programs ? What…
The current study is being conducted to determine whether long-term dual-antiplatelet therapy with ticagrelor in combination with ASA (recommended daily dose 75-100 mg) is beneficial in patients with history of MI (1-3 years ago) and additional risk…
To evaluate the effect of surgical decompression of the nerves in the lower extremities in patients with painful diabetic neuropathy.
The primary objective of this study is to evaluate the PK of POS administered orally at three dosage levels to immunocompromised children with expected neutropenia (selected oncology patients, aplastic anemia patients and patients which undergo a…
The primary objective is the safety and feasibility of CEA/frameshift derived neopeptide loaded DC in patient with MSI-positive colorectal cancer and persons who are known to be carrier of a germline MMR-gene mutation with no signs of disease yet.…
Main question: p. 12 of proposalIs the online psycho-educative prevention program Kopstoring a (cost) effective program for children of parents with mental or substance use disorders to reduce their symptoms (primarily reduction of internalising and…
To evaluate the efficacy of metformin 500mg 2dd1 treatment compared with placebo 2dd1 in adjunction to optimal reperfusion therapy for acute MI on left ventricular ejection fraction at 4 months.
What is the correlation between change in Mannitol PD15 (provoking dose of mannitol to cause a >= 15% fall in FEV1 ) 6h after a single dose of beclomethasone and after 4 weeks of treatment with beclomethasone?
To assess the costs and effects of tailoring the duration of elastic compression stocking (ECS) therapy after deep vein thrombosis (DVT) to individual patients needs.
Driven by the hypothesis that combination of dietary polyphenols, with distinct mechanisms of action, may improve cellular energy and fatty acid metabolism, preventing thereby the development of the metabolic syndrome and diabetes, the following…
The current research proposal aims to investigate the medium and long-term health benefits of a combined supervised exercise and dietary intervention versus a dietary intervention (=usual care) in obese long-standing type 2 diabetes patients. It is…
The purpose of this clinical pilot study is to generate quantitative evidence that the oral administration of 80 mg Simvastatin per day, three weeks before surgery and one week thereafter, will have a significant effect on fibrinolytic activity…
To evaluate whether (I) buttermilk lowers serum LDL-cholesterol concentrations and as such (II) can prevent the serum LDL-cholesterol raising effects of eggs.
To assess the preemptive effect of Bepanthen® on decreasing the incidence of specific >= grade 2 dermatological side effects of interest in respect of compliance to EGFRI agents, HRQoL and the adherence during the 6-week skin treatment period…
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. Selection of candidates from surgery is based mainly on duplex ultrasonography, where now only the size of the stenosis is…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
To compare the efficacy of playing Tetris to Assessments Only in the reduction of frequency, vividness, and emotional intensity of intrusions in Dutch soldiers exposed to aversive events on deployment in Afghanistan.
The main objective of this observational study is to examine DPA in HF patients (NYHA II and III) by means of accelerometry. The secondary objective is to assess the influence of a number of psychosocial determinants (e.g. self-efficacy, intrinsic…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…