16 results
Vapor ablation can effectively and safely eradicate short BE segments
In patients with recently diagnosed PMR, MTX 25mg/week compared to placebo will lead to a higher proportion of patients in glucocorticoid free remission
To assess the PK/PD relationship of prednisolone as either prophylaxis or therapy of GVHD in children after HCT.
Investigate the effect of having CYP2C19 and CYP2D6 genotypes at start of antidepressant therapy and it’s cost-effectiveness in the primary care setting.
Primary Objective: To investigate whether timely delivery of iCBT will lead to a significantly lower mean fatigue severity score (CIS-fatigue) across follow-up visits (T1 and T2) as compared to care as usual. Secondary Objectives: To investigate…
Major burns encompassing more than 15-20% of total body surface area (TBSA) induce a pathophysiological stress response and thereby massive inflammatory response. Patients with major burns develop metabolic changes and burn induced hypermetabolism,…
Postoperative NRS pain scores in the breast after BCS are lower in women who receive a preoperative PECS II block than in women who receive a sham block.
the application of EMDR therapy is associated with a significant decrease in severity of depressive symptoms and decrease of percentage of patients meeting DSM-5 criteria for MDD compared to the waiting list. Participants receiving EMDR report after…
Is a 6-month PRET program effective in reducing CVRF diabetes mellitus type 2(HbA1c FG), in adults with mild to moderate ID. Secondary Objective(s): Is a 6-month PRET program effective in reducing other CVRF: hypertension (SBP, DBP),…
The main objective of the study is to assess the change in first morning void urine albumin-to-creatinine ratio across the study period. The secondary objective is to assess changes from baseline in systolic blood pressure, body weight, eGFR and…
The study objective of the trial was to test the hypothesis that treatment with mepolizumab only affects inflammatory eosinophils whereas treatment with benralizumab affects both inflammatory and resident eosinophils.
The quality of life of adult patients with NMD can be enhanced by providing capability care in comparison to usual care.
As this is an explorative design, no formal hypothesis is made. However, our sample size is based on a difference of 2.5% or more in cumulative incidence of serious infections when continuing IA, hypothesizing that patients who continue their IA in…
Based on the results of EMDR studies in older children aged 8-18 years and adults, it is hypothesized that EMDR will lead to reductions in post-traumatic stress symptoms, co-morbid emotional and behavioral problems. Additionally, we expect that EMDR…
Primary Objective: - Achieving an event-free survival, which is not inferior to the ML-DS 2006 trial (87±3%) Secondary Objective(s): - Reduction of toxicity: severe adverse events (CTCAE v4.0 grade III or higher) - Evaluation of…
We hypothesize that the fertility enhancing effect of OSCM during HSGs is also present during THL.