4 results
The primary objective of the study is:- To evaluate the pharmacodynamics effects on follicular growth and ovulation of one dose of 30 mg UPA taken before dominant follicle selectionThe secondary objectives are:- To determine the pharmacokinetics…
Primary:To evaluate the probability that FNA successfully obtains liver tissue specimens from which to evaluate liver drug concentrationsSecondary:1. To characterize the steady-state hepatic pharmacokinetics of MK-7009 (e.g., area under the liver…
The purpose of the study is to compare the efficacy of talquetamab subcutaneous(ly) (SC) in combination with daratumumab SC and pomalidomide (Tal-DP) and talquetamab SC in combination with daratumumab SC (Tal-D), respectively, with daratumumab in…
Primary- Part 1: To identify recommended Phase 2 doses and schedules (RP2Ds) for each combination.- Part 2: To characterize the safety of each RP2D for each combinationSecondary- To characterize the pharmacokinetics and pharmacodynamics of each…