3 results
Primary objectivesThe primary objective of the study is demonstrate that at least one of the sotrastaurin treatment arms is non-inferior to the active control regimen myfortic + tacrolimus with respect to composite efficacy failure (treated BPAR of…
Primary objective: Estimate the added value of using hydrogel in addition to clips only in terms of the Conformity Index (Cx) of tumorbed delineationSecondary objectives: Estimate the Cavity Visualisation Score (CVS), distance between the center of…
Estimate the maximum tolerated dose (MTD) of AEB071 (dose escalation) and characterize the safety and tolerability of the MTD or recommended Phase 2 dose of AEB071 in patients with metastatic uveal melanoma (dose expansion).