5 results
Primary objectivesThe primary objective of the study is demonstrate that at least one of the sotrastaurin treatment arms is non-inferior to the active control regimen myfortic + tacrolimus with respect to composite efficacy failure (treated BPAR of…
Estimate the maximum tolerated dose (MTD) of AEB071 (dose escalation) and characterize the safety and tolerability of the MTD or recommended Phase 2 dose of AEB071 in patients with metastatic uveal melanoma (dose expansion).
Relate aneurysm hemodynamics to aneurysm configuration and growth to obtain insight in the hemodynamic pathophysiology of aneurysm growth in order to improve prediction of aneurysm rupture.
Primary Objective: To confirm that the lithium headcoil is capable of measuring lithium signals related to clinical doses in the brains of BD patients (MDR, art 82), and then to establish the correlation of neuroimaging data of lithium…
To characterize glioma and epileptogenic tissue with 7T metabolic MRI, and validate their metabolic imaging characteristics with histopathological measures.