6 results
The specific goals of the study are:- To identify which dose(s) of mecamylamine cause cognitive and memory impairment as demonstrated using the NeuroCart CNS test battery- To investigate the safety and tolerability of mecamylamine by comparison with…
Primary Objectives:• Assess the pharmacokinetic (PK) and pharmacodynamic (PD)/efficacy effects of 3 different single doses of EVP-6124 vs. placebo;• Assess the PK and PD/efficacy effects of the different combinations of 2 doses of donepezil and 3…
The aim of the substudy is the identification of early (baseline) predictors of heart failure during a relatively high frequency of electrical stiumulation of the right ventricle. How does heart function change over a period of 2 years which…
- To determine the effects of the pacing site on prevention of AF episodes - To examine the relation between the pacing site, reduction of AF episodes, quality of life, heart failure, number of cardioversions, frequency and duration of hospital…
The primary objective of this study is to compare in a randomized trial the effects of permanent LVSP with RVP in patients with a pacemaker indication because of AV conduction disorders, with respect to a composite of all-cause mortality,…
The primary objective is to test whether rhythmic somatosensory input (vibrotactile stimulation at tremor frequency) reduces tremor power of Parkinson*s tremor, as compared to other vibrotactile stimulation settings (continuous stimulation,…