8 results
This research project aims to investigate whether hyperoxic interval training improves whole body insulin resistance, endothelial dysfunction, cardiovascular fitness, lipid metabolism and glycemic control in the treatment of deconditioned non-…
Primary objectiveTo compare the wear rate 60 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty. Secondary objectives- To compare the wear rate at 3,12, 24 and 60 months after THA between…
Primary Objectives• To describe the anti-tumor activity and toxicity of commercially available, targeted anti-cancer drugs used for treatment of patients with an advanced solid tumor, multiple myeloma or non-Hodgkin lymphoma that harbours a genomic…
To determine the median progression-free survival (PFS) and R0/1 secondary resection rate upon induction systemic treatment in colorectal cancer patients with initially unresectable liver-only metastases, stratified by RAS and BRAF tumor mutation…
- Primary Objective:To evaluate the safety and tolerability of investigational regimens of sotorasib in adult subjects with KRAS p.G12C mutant advanced solid tumors- Secondary Objectives:To characterize PK of product(s) used in investigational…
The aim of the phase Ib part is to estimate the MTD and/or identify the RP2D for the combination MEK162 and panitumumab, followed by a phase II part to assess the clinical efficacy and to further assess the safety of the combination in selected…
To study the relation between PaO2/FiO2-ratio and FiO2
The objective of this study is to investigate whether hyperbaric oxygen therapy twice-daily for five days (HBOT5) is superior to hyperbaric oxygen therapy once daily for ten days (HBOT10) in obtaining hearing loss recovery after AAT. This will be…