3 results
Approved WMOCompleted
The primary objective is to determine an effect of sleep deprivation on CSF Aβ42 levels in humans.Secondary objectives: -Effect of unrestricted sleep on CSF Aβ42 levels.-Effects of unrestricted sleep and sleep deprivation on other known AD…
Approved WMOCompleted
This drug-drug interaction (DDI) study is being conducted to determine if there is a pharmacokinetic (PK) interaction between trametinib and the components of combination oral contraceptives (OCs), norethindrone (NE) and ethinyl estradiol (EE).…
Approved WMOCompleted
To determine the influence of concomitant administration of tamoxifen and probenecid on tamoxifen and endoxifen(-glucuronide) plasma concentrations