3 results
Primary Objectives• Safety and tolerability• PK of OCA and its conjugates o SD PK Phase: To assess the PK of OCA and its conjugates after a single low dose of OCA on Day 1 and determine subject eligibility for the MD Phase o MD Phase: To assess the…
To evaluate the immediate impact of TAVI or TMVr on a battery of coronary (non-) hyperemic physiology tests in patient with severe aortic valve stenosis or functional/degenerative mitral regurgitation and at least intermediate coronary artery…
The primary objective is to assess the effects of the combination of OCA and BZF on alkaline phosphatase(ALP) in comparison to BZF alone in subjects with primary biliary cholangitis (PBC)To assess the effects of the combination of OCA and BZF in…