3 results
This study is therefore aimed at quantifying the relative contribution of the two major receptor systems involved in S(+)-ketamine and methadone induced analgesia and side effects (respiratory depression, sedation, miosis).
Primary objective: To evaluate the optimum comfortable on-demand humidification doses for neuromuscular patients requiring chronic mechanical ventilation using subjective as well as objective measurements of the optimum comfort.
The goal of the studies is multiple:1. To describe the pharmacokinetics of intravenously administered fentanyl and sufentanil;2. To describe the pharmacodynamics of intravenously administered fentanyl and sufentanil (important model parameters…