2 results
Approved WMOCompleted
1. Determine the influence of acetylcysteine on thiopuirine related hepatotoxicity2. Determine the relation between hepatotoxicity, thiopurine metabolism, amino acid availablility and markers for oxidative stress3. Determine the effect of…
Approved WMOCompleted
to confirm that GMC 252 is absorbed in humansto determine in humans whether GMC 252 is cleaved, yielding diflunisal and N-acetylcysteine (NAC)to determine whether additional metabolites are formed with GMC-252 compared with diflunisal and NAC