10 results
Primary objective: The primary objective of the study is to determine the effect of oral dipyridamole treatment on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Various pro- and anti-inflammatory cytokines will be…
Main study:1. Does blockade of the angiotensin II AT1-receptor improve the insulin-induced microvascular effects in hypertensive patients.2. Does blockade of the angiotensin II AT1-receptor impair the insulin-induced mi-crovascular effects in…
The objective is to analyze whether a difference in reservecapacity is present between short-term and long-term PD patients. In case the reservecapacity of the peritoneum is significantly lower in the long-term compared to short-term PD patients, a…
1.) First, we hypothesize that a reduction of myocardial damage explained by lower levels of myocardial damage markers (e.g. troponin I, CK-MB) by sevoflurane may be related to a reduction of inflammatory mediators (i.e. TNF-α, CD11b/CD18 cells, and…
We aim to study the vasoactive effects of Acetylcholine (NO dependent) in hypertensive patients and normotensive participants. Second, the correlation between the vasoreactivity of Acetylcholine and Angiotensin II will be studied. Third, the…
The objective is to investigate the effectiveness of an Internet-based self-help intervention for people with mild symptoms of anxiety and/or depression. This intervention will be offered with and without guidance and will be compared to usual care…
The objectives of the study are to assess whether:(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low-dose ketamine;(2) SNP will reduce the ketamine-induced increase in blood pressure and cardiac output;(3) SNP is…
Objective: To investigate the feasibility and acceptability of the online cognitive behavioral therapy program (eHealth CF-CGT), so that the program can be tailored to the needs of the patient
To investigate the efficacy of bCBT compared to usual care in severely fatigued patients with primary brain tumors.
The aims of this project are to 1) to determine the non-inferiority of inter-CBT, compared to a benchmark study where CBT was provided by psychologists (TIRED study), in its effect on reduction in cancer-related fatigue, 2) to adapt CBT delivery to…