4 results
This drug-drug interaction (DDI) study is being conducted to determine if there is a pharmacokinetic (PK) interaction between trametinib and the components of combination oral contraceptives (OCs), norethindrone (NE) and ethinyl estradiol (EE).…
To determine the amount of rotational instability in trochanteric femoral fractures, related to type of implant and fracture.The primary goal is to evaluate differences in fracture micromotion (i.e. translation and rotation) between different…
To determine the amount of in fracture micromotion (i.e. rotation and translation) in femoral neck fractures, related to type of used implant: a DHS or 3 cannulated hip screws.The secondary objective is to relate the micromotion to bone density, and…
Primary objectiveTo evaluate if tralokinumab after 14 weeks of treatment (at steady state) changes the metabolism of substrates of CYP 1A2, 2C9, 2C19, 2D6, or 3A4 pathways in subjects with moderate-tosevere atopic dermatitisSecondary objectivesTo…