3 results
Phase 1Primary Objective• To determine the RP2D and, if applicable, the maximum tolerated dose (MTD) of NVL-520 in patients with advanced ROS1-positive solid tumorPhase 2Primary Objective• To evaluate the ORR of NVL-520 at the RP2D in patients with…
The purpose of this study is to characterize the safety and tolerability of OAV101 IT in participants who have discontinued treatment with nusinersen (Spinraza®) or risdiplam (Evrysdi®). The data from this study will expand on the data generated…
The purpose of this trial is to evaluate the safety and effectiveness of the Medtronic Evolut PRO+ and Evolut FX TAVR system and guideline-directed management and therapy (GDMT) compared to GDMT in patients with moderate, symptomatic AS. Data will…