3 results
The study is designed to substantiate the efficacy of CCM in the heart failure population with ejection fraction ranging between 25 and 45%. The study is designed in an adaptive manner to ensure proper statistical significance and power of the…
Primary:To assess the safety and tolerability of MCLA-117, in order to determine the MTD/RP2D and frequency of administration.Secondary:- To assess the pharmacokinetic (PK) profile of MCLA-117 i.v. infusion- To investigate the pharmacodynamic (PD)…
Primary objective of this study is to enhance insight in differences in elemental cardiovascular physiology between different levels of VA-ECMO support, by comparing pressure-volume loop derived parameters between 4.0-3.0-2.0-1.0-0.5 L/min…