3 results
Primary- To determine the validity of home-based self-monitoring of VC in patients with MND.Secondary- To determine the reliability of home-based self-monitoring of VC in patients with MND.- To evaluate the feasibility of 4-weekly home-based self-…
Primary Objective:Part A:To evaluate the efficacy of losmapimod for the treatment of FSHD by demonstrating slowing of disease progression assessed by reachable workspace quantification of total relative surface area (RSA) Q1-Q5 with 500 g wrist…
To characterize the safety, tolerability, and recommended phase 2 dose (RP2D) of each combination partner used with ruxolitinib (Part 1)To evaluate the preliminary efficacy of each novel ruxolitinib combination treatment arm (Parts 2 & 3)