5 results
Primary: To evaluate the effect of MBX-8025 on LDL-C.Secondary: To evaluate the effects of MBX-8025 on other lipid parametersTo evaluate the safety and tolerability of MBX-8025.To evaluate steady-state trough plasma levels of MBX-8025 and its…
Primary:To evaluate the effect of MBX-8025 on LDL-C.Secondary:To evaluate the effects of MBX-8025 on other lipid parameters. To evaluate the safety and tolerability of MBX-8025. To evaluate steady-state trough plasma levels of MBX-8025 and its…
To determine the effect of lithium treatment (plasma levels between 0,4-0,8 mEq/liter) versus placebo - in addition to riluzole 2dd 50 mg - on reaching a clinical endpoint in patients with ALS.
To investigate the efficacy and safety of drugs for patients with ALS.
1. Is PmsALG comparable with PmsINSP, even with changing Ppl?2. Is PmsARM comparable with PmsINSP and PmsALG?3. Does thoracic drainage have influence on pleural pressures measured by esophageal balloon catheter to determine transpulmonary pressure?4…