5 results
Part 1A:Primary objective is to evaluate the safety and tolerability of ascending single doses of TDT 077 in healthy older male and female subjects. Secondary objective is to evaluate the systemic exposure (PK) of ascending single doses of TDT 077…
This study is therefore aimed at quantifying the relative contribution of the two major receptor systems involved in S(+)-ketamine and methadone induced analgesia and side effects (respiratory depression, sedation, miosis).
The primary objective of this study is to compare effectivity of suboxone and methadone on reducing opioid misuse.Secondary objectives include comparing the effects of these two medications on pain, well-being and medication use.
The primary objective of this study is to compare the acute effects of single doses of methadone (5 and 10 mg) and buprenorphine (0.2 and 0.4 mg) with placebo on driving performance and cognition. Secondary objective is to study the pharmacokinetics…
The main objective in this study is whether biofeedback on the psychofysiological stress level is effective in reducing incidents in youth in residential care.