4 results
Primary objectivesThe primary objective of the study is demonstrate that at least one of the sotrastaurin treatment arms is non-inferior to the active control regimen myfortic + tacrolimus with respect to composite efficacy failure (treated BPAR of…
Estimate the maximum tolerated dose (MTD) of AEB071 (dose escalation) and characterize the safety and tolerability of the MTD or recommended Phase 2 dose of AEB071 in patients with metastatic uveal melanoma (dose expansion).
The goal of this study is to evaluate if serum FGF23 levels are directly related to cardiovascular calcification, measured as arterial stiffness with pulse wave velocity. The primary objective is to evaluate if elevated serum FGF23 and decreased…
To demonstrate the safety and efficacy of the Latella Knee Implant System for the reduction of medial osteoarthritis knee pain