7 results
Primary ObjectiveThe primary objective of this study is to assess whether the antidepressant response to IV ketamine can be maintained by minocycline compared to placebo.Secondary ObjectivesThe secondary objectives of this study are:* To investigate…
The objectives are to assess the pharmacokinetic and pharmacodynamic effects of sub-anesthetic ketamine administration, to assess the optimal dose of ketamine and gender differences, to compare different oucome measures for psychomimetic symptoms…
The effectiveness an cost effectiveness of PPIs compared to standard phlebotomy therapy in the prevention of iron overload in patients with hereditary hemochromatosis.
To study the influence of omeprazole and pantoprazole on the platelet reactivity index and the inhibition of platelet aggregation by clopidogrel.
Primary objectiveTo evaluate the CNS effects of a single intravenous dose of ketamine on functional brain networks by performing resting state functional magnetic resonance imaging (fMRI) in major depressive disorder (MDD) patients who fail to…
In this study we want to investigate how a perturbation-based treadmill training with cognitive dual-task improves daily life gait stability in older adults compared to conventional treadmill training with cognitive dual-task.The results of this…
The primary objective of the study is to determine whether TAK-653, in comparison to placebo, increases CNS excitability, assessed with TMS-evoked MEP in healthy subjects.Next to that, the study has the following goals: - To determine whether TAK-…