5 results
Primary objective:To determine the MTD/recommended dose for further study of oral LOXO-292 in patients with advanced solid tumors, including RET-fusion NSCLC, MTC, and other tumors with increased RET activity.Secondary objectives:* To determine the…
Primary* To compare TFFS of patients with progressive, advanced, kinase inhibitor naïve, RET-mutant MTC treated with LOXO-292 versus cabozantinib or vandetanib.Secondary* To compare other efficacy outcomes, based on RECIST 1.1 criteria, observed in…
To assess the safety and efficacy of a *minimally-invasive upper extremity* approach (radial artery for pigtail catheter and brachial vein for temporary pacemaker when not pacing over the left ventricular stiff wire OR radial artery and pacing over…
To compare PFS of patients with progressive, advanced, kinase inhibitor naïve, RET-mutant MTC treated with selpercatinib versus cabozantinib or vandetanib.
Primary Objective:Patient-specific full geometry assessment of abdominal aortic aneurysms (AAA). The assessment includes the shape and thickness of the intraluminal thrombus and the aortic wall.Secondary Objective(s): IVUS-based assessment of tissue…