26 results
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
The primary efficacy variable is the change in PV from baseline as assessed by 3 D ultrasonography after 78 weeks of double-blind treatment with OM 20-40 mg daily compared to ATE 50-100 mg daily.Secondary efficacy variables:Change from baseline PV…
Determinination of the added effects of dietary sodium restriction or diuretic use to antihypertensive and antialbuminuric therapy.
To investigate that in mamma surgery, regional infiltration with ropivacaine 0,75% added to general anaesthesia causes less postoperative pain, nausea and vomiting compared to general anaesthesia alone.
Primary: Period II (Week 8 to Week 16)1. To demonstrate the additional antihypertensive efficacy for seated diastolic blood pressure (SeDBP) gained by adding HCTZ 12.5 or 25 mg to the treatment regimen in subjects with moderate to severe HTN not…
Main objective: * To evaluate the effect and variation of 3 and 12 months treatment with Aliskeren-based versus amlodipine-based antihypertensive treatment on aneurismal FDG- uptakeExploratory objectives: * To explore the effect of 3 and 12 months…
1.To evaluate the influence of epidural blockade with ropivacaine on the pharmacokinetics of propofol.2.To evaluate the influence of epidural blockade with ropivacaine on the pharmacodynamics of propofol. This includes both the sedative and the…
The researchquestions of this study are:1. What is the efficacy of treatment of postoperative pain after subacromial decompression with a subacromial catheter with ropivacaine versus placebo?2. What are the differences in costs per patient and in…
Primary objective: to compare changes in endothelial function in patients with obesity related hypertension after 8 weeks of treatment with aliskiren, moxonidine and HCTZ.Secondary objectives: to compare changes in the following parameters in…
1. Less experience of pain by using TLA unlike lidocaine/epinephrine 1 %.2. Little intraoperative bleeding because of the vasoconstrictive effect of TLA.3. Long lasting analgesia, also postoperative.
The main purpose of this project is to investigate the conditions under which blood transfusions are successful in promoting microcirculatory circulation and oxygenation in anemic intensive care patients and the functional effects of storage on red…
The objective of this study is to determine whether either a femoral nerve block (FNB) or local infiltration analgesia (LIA) is a better anesthetic technique to achieve optimal functional outcome after one year in patients receiving a total knee…
The primary objective of this study is to describe a pharmacokinetic profile of bound and unbound plasma concentrations of ropivacaïne, when used in the LIA technique for the knee. Especially describing the Cmax and Tmax gives arguments for dosage…
This prospective randomized controlled trial designed to compare the quality of analgesia offered by SFNB and LIA and their effects on morphine consumption, mobilization and pain control postoperatively. Our first hypothesis concerning opioid use is…
The purpose of the present study is to obtain a pharmacokinetic profile of ropivacaine in serum with epinephrine, and of ropivacaine in serum without epinephrine, used for high dosed combined femoral and sciatic nerve block in lower extremity…
The purpose of the present study is to investigate whether there is a relation between the minimal current at the tip of the stimulating catheter necessary to elicit an appropriate motor response, and the efficacy of the PNB catheter.
Het bestuderen en vergelijken van cocaïne, tetracaïne-oxymetazoline en ropivacaïne-oxymetazoline wat betreft de peroperatieve decongestie en hemostasis en postoperatieve analgesie die zij bieden bij FESS. Study and compare the peroperative…
to compare the analgesic efficacy of levobupivacaine and ropivacaine in patient-controlled epidural analgesia, as assessed by the number of requests for epidural bolus injectionsto compare visual analogue scale (VAS) scores and neural block…
To compare the effect of amiloride on lithium-induced Nephrogenic Diabetes Insipidus with the effect of hydrochlorothiazide, measured as urine volume and maximal urine osmolality.
To demonstrate whether hydrochlorothiazide or metformin can diminish aquaresis in patients with ADPKD who are treated with tolvaptan as measured by 24-hour urine volume.