2 results
Approved WMOCompleted
Primary Objective• To evaluate the efficacy and safety of ustekinumab in pediatric subjects aged >=6 through <12 years with moderate to severe chronic plaque psoriasis.Major Secondary Objectives• To evaluate the pharmacokinetics (PK)…
Approved WMOCompleted
Protein arginine methyltransferases (PRMTs) are a subset of enzymes that methylate arginine residues in various cellular proteins including splicing factors, transcription factors, and histone tails. One of these PRMTs, PRMT5, is aberrantly…