3 results
Approved WMOCompleted
Protein arginine methyltransferases (PRMTs) are a subset of enzymes that methylate arginine residues in various cellular proteins including splicing factors, transcription factors, and histone tails. One of these PRMTs, PRMT5, is aberrantly…
Approved WMOCompleted
The purposes of this study are to study the effects of low-frequency NMES, high-frequency NMES and resistance training on health status, exercise tolerance and muscle strength in patients with COPD.
Approved WMOCompleted
Primary Objective• To evaluate the efficacy and safety of ustekinumab in pediatric subjects aged >=6 through <12 years with moderate to severe chronic plaque psoriasis.Major Secondary Objectives• To evaluate the pharmacokinetics (PK)…