3 results
Approved WMOCompleted
In this study we want to determine the activity and safety of concurrent interruption of the MAPK and PI3K pathways by the EGFR tyrosine kinase inhibitor erlotinb and metformin, combined with gemcitabine in patients with metatastatic pancreatic…
Approved WMOCompleted
The aim of this study is to compare the PD20 values measured with the Vilbiss 646 jet nebulizer protocol and with the MedicAid nebulizing protocol in 20 subjects with respiratory symptoms suggestive of bronchial hyperreactivity.
Approved WMOCompleted
To determine the dose limiting toxicity (DLT) and the maximum tolerated dose and recommended dose of the combination of everolimus orally once daily and metformin orally BID to patients with advanced solid tumors.