2 results
Approved WMORecruiting
To what extend should a possible worsening of the OSA condition, caused by an increase of mouth opening and partial palatinal coverage, be taken into consideration in daily dental practice, when an occlusal splint is placed in the mouth.Amendement:…
Approved WMORecruiting
Dose escalation phase:Primary• Determine the RP2D and if reached, the MTD of GEN3014• Evaluate the safety and tolerability of GEN3014 Secondary:• Characterize the PK properties of GEN3014• Characterize the pharmacodynamic properties of GEN3014•…