4 results
1. To assess tolerability and safety of BAX 826 after a single infusion in previously PTPs with severe hemophilia A.2. To determine the pharmacokinetic (PK) parameters of BAX 826 compared to ADVATE.3. To evaluate the impact of anti- PSA antibodies…
reduction of fluid administration of 30%
1. Is PmsALG comparable with PmsINSP, even with changing Ppl?2. Is PmsARM comparable with PmsINSP and PmsALG?3. Does thoracic drainage have influence on pleural pressures measured by esophageal balloon catheter to determine transpulmonary pressure?4…
The primary objectives are to determine the maximum tolerated dose (MTD) and/or recommended phase two dose (RP2D) of ABBV-621 and to evaluate pharmacokinetics (PK) of (A) single agent ABBV-621; and (B) the combination of ABBV-621 and venetoclax in…