4 results
Primary ObjectiveTo determine the influence of treatment for OSA opioid-induced respiratory depression (minute ventilation (Vi); tidal volume (Vt); respiratory rate (RR); end-tidal pCO2; SpO2).Secondary ObjectivesAim 2: To determine the influence ofā¦
The aim of the main study is to compare the effects of MR30365/07 and fentanyl on ventilation and analgesic responses to noxious electrical and heat stimulation in healthy volunteers, by performing pharmacokinetic / pharmacodynamics (PK/PD) modelingā¦
This study will evaluate the effectiveness of DRG neurostimulation for treating chronic groin pain and capture pilot data regarding the mechanisms of DRG neurostimulation.
This study is intended to establish a dose response rate of MR30507/09 with respect to respiratory effects compared to MR30365/07, fentanyl and placebo..