2 results
Approved WMOCompleted
* To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use;* To determine if therapeutic concentrations achieved with…
Approved WMORecruiting
There are two main objectives for this study. First, we will investigate the following hypothesis: Fentanyl patches provide reduction of dyspnea compared to placebo, comparable to morphine, and with less side effects than morphine. Secondly, with…