6 results
The main objective of this pilot study is to determine intratumoral concentrations of kinase inhibitors upon 2 weeks of treatment in tumor tissue of patients.
Primary objectiveTo evaluate the effect of PK-guided individualized dosing of pazopanib on the interindividual variability in drug exposure.Secondary objective- To determine the correlation between pazopanib trough and exposure levels - To determine…
The first aim of this study is to identify factors which predict an improvement of gastroesophageal reflux after gastric banding. The second aim is to assess the effect of gastric banding on gastroesophageal reflux after the operation.
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
To compare the therapeutic benefit of maintenance pazopanib versus placebo after first line treatment of NSCLC.
The main objective of this pilot study is to determine the biological impact of treatment with targeted agents at the systemic and local tissue level in relation to toxicity.