4 results
To assess the feasibility and safety of using a combined sponge-methylation biomarker strategy in detection of Barrett*s Esophagus, (early) esophageal cancer and detection of locoregional regrowth after nCRT.
Primary Objectives• Safety and tolerability• PK of OCA and its conjugates o SD PK Phase: To assess the PK of OCA and its conjugates after a single low dose of OCA on Day 1 and determine subject eligibility for the MD Phase o MD Phase: To assess the…
Studies to date have demonstrated a reduction in HF-related hospitalizations and improved quality of life in patients using the CardioMEMS HF System when compared with patients receiving standard of care in the United States. The purpose of this…
The primary objective is to assess the effects of the combination of OCA and BZF on alkaline phosphatase(ALP) in comparison to BZF alone in subjects with primary biliary cholangitis (PBC)To assess the effects of the combination of OCA and BZF in…