4 results
Primary objective: To determine the pharmacokinetic profile of lopinavir and ritonavir in two differ-ent co-formulations (Lopimune granules and Lopimune tablets) after single-dose in HIV-negative, healthy adult subjects, and to compare this to the…
Primary objective:- To evaluate dose modifications of the new Kaletra Meltrex tablets (lopi-navir/ritonavir 200/50 mg) when combined with rifampicin in healthy volunteersSecondary objectives:- To evaluate the safety of combined use of the new…
Primary ObjectivesDose Escalation Phase* To determine the maximum tolerated dose (MTD) of multiple ERY974 dosing schedules, including fixed dose schedules and an individual dose titration schedule, in patients with locally advanced or metastatic…
The main purpose of this study is to assess the impact of arterial stiffness on the response in 24h ambulatory blood pressure reduction following renal sympathetic denervation in patients with primary hypertension with or without diastolic…