4 results
The primary objective is to evaluate the feasibility of early therapeutic effect evaluation by performing early follow up imaging after percutaneous MR-guided cryoablation of pT1a renal cell carcinoma. Secondary objective is to assess the outcomes…
Primary Part 1:-To evaluate ORR in participants treated with MK-4280A plus EV (Arm A), MK-7684A plus EV (Arm B), and pembrolizumab plus EV(Arm C) per RECIST 1.1 by BICR.- To evaluate the safety and tolerability in participants treated with MK-4280A…
To study the safety and efficacy of mitapivat in the treatment of adult subjects with sickle cell disease.
Identification of MRI-based biomarkers to predict clinical outcome of major depressive disorder in comparison with healthy controls. Outcome is defined by level of depressive and cognitive symptomatology and related comorbidity.