9 results
Study Rationale and ObjectivesThe objective of the study is to determine the efficacy and safety of lacosamide, a sodium channel blocker, in patients with pain due to SCN9A-associated SFN. The proposed study plans to recruit patients with clinically…
Primary objective:The primary objective of this study is to evaluate the effect of LCM 200mg bid on the single dose PK and PD of a single warfarin 25mg dose.Secondary objective:The secondary objective of this study is to monitor the safety and…
The primary objective of this study is to assess the overall effectiveness of LCM (optimizedwithin the range of 200mg/day to 600mg/day) when added to a stable dose of LEV (in thelabel range of 1000mg/day to 3000mg/day) with withdrawal of the…
Aim of the present study is to assess normal values of EGJ distensibility in healthy volunteers.
Primary Objective- To evaluate the feasibility and test-retest variability of nerve excitability threshold tracking - To investigate the sensitivity of nerve excitability measures to detect the effects of mexiletine- To investigate the sensitivity…
Primary objectives 1. To evaluate the efficacy, feasibility and safety of G-POEM in patients with symptoms delayed gastric emptying after oesophagectomy with gastric tube reconstruction, based subsequently on the clinical success rate at 3 months,…
To assess whether lacosamide is as efficient in the treatment of chemotherapy-induced neuropathic pain as duloxetine
This study is to answer two questions. First the reliability and validity of the novel lavage method to screen on cervical cancer in combination with the clinically validated hrHPV and hypermethylation triage tests. Second the functionality and…
The objective of the study is to quantify the effect of pregabaline and lacosamide on oxycodone-induced respiratory depression.