6 results
Primary objectiveTo determine whether individualized pharmacokinetic (PK)-guided dosing of emicizumab is non-inferior to conventional dosing of emicizumab in the - proportion of patients without treated bleeds (6 months before and after intervention…
Study MO41787 will evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab administered at 3 mg/kg Q2W for a period of 52 weeks in previously untreated patients (PUPs) and minimally treated patients (MTPs) at study…
The study will investigate the safety and efficacy of emicizumab in patients with hemophilia A with inhibitors against FVIII.
The objective of this study is to validate a new patented prototype prosthetic leg on lateral balance control, and to gain insight into lateral balance in prosthetic walking.The following research questions will be investigated:1. What differences…
This study will evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of emicizumab in patients of all ages with mild (FVIII level between > 5% and < 40%) or moderate hemophilia A (FVIII level between >= 1% and…
The main objective of this study is to demonstrate treatment efficacy of MR-HIFU ablation of breast cancer. Effective treatment is defined as 100% necrosis of the targeted primary breast tumor. The secondary objective is safety of the MR-HIFU…