15 results
The objective of this study is to assess the effects of a single and chronic oral administration of S 44121 versus placebo on the occurrence of cardiac arrhythmia during standardized exercise tests (ETs) in patients with CPVT type 1. The safety…
To establish the drug drug interaction of paracetamol with propranolol and the effect of this interaction on the pharmacokinetic profile and metabolites of paracetamol.
• To elucidate the role of noradrenaline in the mechanisms involved in human memory consolidation• Evaluate the levels of cortisol and 3-methoxy-4-hydroxyphenylglycol in the various points of a memory consolidation window• Define pharmacological…
The aim of the study is to examine the effect of propranolol on intrusive memories of people suffering from a specific phobia (i.e. dental phobia). It is hypothesized that the administration of propranolol prior to dental treatment:1. would be…
The aim of this study is to evaluate the anti-arrhythmic efficacy of S 44121 versus placebo administered orally for a total of 12 weeks in patients with chronic heart failure and left ventricular systolic dysfunction who received an implanted…
The purpose of the study is to compare the combination of DEB/BMS versus DES versus BMS alone in patients with an AMI.
The objective is to study the effect of beta-agonist and beta-antagonist treatment on human bone remodeling.
To anwer the question: Is the elevation of energy expenditure and mitochondrial uncoupling smaller in obese than in lean subjects after mild cold exposure and what is the role of the sympathetic nervous system?
Evaluation of provisional T stenting using a bare metal stent in combination with a paclitaxel eluting balloon compared with a normal balloon. And comparing a bare metal stent in combination with a paclitaxel eluting balloon with a paclitaxel elutin…
To study nocturnal FFA rhythm with or without *-blockers in insulin resistant subjects and healthy controls.
To evaluate whether acute stress induced by a byngy jump alters the status of the innate immune system
The aim of this study is to determine the effects of propranolol on patients* crucial fear-related memories and dental trait anxiety in those undergoing surgical removal of one of their teeth or molars. The hypotheses that are tested are that…
Our aim is to test whether disrupting the process of fear memory reconsolidation is an effective as well as efficient intervention for patients with panic disorder. A secondary aim is to test whether the expected reduction in panic attacks and…
The goal of the present study is to investigate whether the blockade of NA-transmission by beta-antagonist propranolol reduces the common EMDR effects (reduced vividness/emotionality of emotional memories) in order to find out if NA-release (evoked…
The primary objective is to determine the clinical response of propranolol monotherapy in patients with angiosarcoma. The secondary endpoint is to assess the pathologic response of propranolol monotherapy in patients with angiosarcoma.